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1. Effect of Aspirin on Disability-free Survival in the Healthy Elderly - 09/16/2018
 The New England Journal of Medicine (Massachusetts Medical Society)
  Aspirin use in healthy elderly persons did not prolong disability-free survival over a period of 5 years but led to a higher rate of major hemorrhage than placebo.
2. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly - 09/16/2018
 The New England Journal of Medicine (Massachusetts Medical Society)
  Higher all-cause mortality was observed among apparently healthy older adults who received daily aspirin than among those who received placebo and was attributed primarily to cancer-related death.
3. Semisynthetic sensor proteins enable metabolic assays at the point of care - 09/14/2018
 Science 14 Sep 2018: Vol. 361, Issue 6407, pp. 1122-1126
  The sensor system successfully generated point-of-care measurements of phenylalanine, glucose, and glutamate. Concentrations of phenylalanine in the blood of phenylketonuria patients were analyzed within minutes with only half a microliter of blood.
4. NIH gets $2 billion boost in final 2019 spending bill - 09/14/2018
 American Association for the Advancement of Science (AAAS)
  By Jocelyn KaiserSep. 14, 2018 Congress has approved a $2 billion raise, to $39.1 billion, for the National Institutes of Health (NIH) in a 2019 spending bill approved by House of Representatives and Senate negotiators last night.
5. Scientists engineer a powerful new weapon against antibiotic-resistant bacteria - 09/12/2018
 American Association for the Advancement of Science (AAAS)
  By Jon Cohen, Sep. 12, 2018 New drug can breach sturdy cell membranes and thwart life-threatening infections
6. As massive Zika vaccine trial struggles, researchers revive plan to intentionally infect humans - 09/12/2018
 American Association for the Advancement of Science (AAAS)
  By Jon Cohen, Sep. 12, 2018
7. Universities are worse than drug companies at reporting clinical trial results - 09/12/2018
 American Association for the Advancement of Science (AAAS)
  By Tania Rabesandratana, Sep. 12, 2018 Almost 90% of academic clinical trials are not reported promptly to European registry
8. Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance - 09/11/2018
 JAMA. 2018;320(10):984-994
  Among patients with E coli or K pneumoniae bloodstream infection and ceftriaxone resistance, definitive treatment with piperacillin-tazobactam compared with meropenem did not result in a noninferior 30-day mortality. These findings do not support use of piperacillin-tazobactam in this setting.
9. How does exercise keep your brain young? - 09/06/2018
 American Association for the Advancement of Science
  A study published today in Science offers some new clues. In mice that mimic a severe, genetic form of Alzheimer'' disease, a combination of treatments that prompt the growth of new brain cells and protect them from damage can mimic the beneficial effects of exercise in preventing memory decline. So could we someday bottle the effects of exercise to treat Alzheimer? And if so, what exactly would we need to bottle? Here is a rundown of what we know, and what is still controversial.
10. New gene-editing treatment might help treat a rare disorder, hints first human test - 09/05/2018
 American Association for the Advancement of Science
  The first test of a new gene-editing tool in people has yielded early clues that the strategy, an infusion that turns the liver into an enzyme factory, could help treat a rare, inherited metabolic disorder.
11. American Cancer Society Selects First Project in New Accelerator Pipeline - 09/04/2018
 American Cancer Society
  Funds and intellectual support aim to help speed medical devices and technology to market
12. Spurred by opioid epidemic, new pain drugs may lower the risk of overdose and addiction - 08/29/2018
 American Association for the Advancement of Science
  As the opioid crisis continues to ravage U.S. communities, scientists and drug companies have intensified their efforts to develop safer and less addictive pain medications.
13. Potential Impact of ACC/AHA Hypertension Guideline on Normotensive CAD Patients - 08/23/2018
 American College of Cardiology (ACC)
  What is the relationship between blood pressure (BP) and cardiovascular events in real-life patients with coronary artery disease (CAD) with newly diagnosed hypertension, based on the 2017 American College of Cardiology/American Heart Associatio...
14. Sarcopenic Obesity and Cardiovascular Disease in Older Adults - 08/23/2018
 American College of Cardiology (ACC)
  Obesity rates defined using body mass index (BMI) exceed 40% in adults aged 65 years and older. However, BMI is a poor measure for the ascertainment of adiposity because its sensitivity drops markedly with increasing age.
15. Impact of PCI on Exercise Hemodynamics in Stable CAD Patients - 08/23/2018
 American College of Cardiology (ACC)
  What is the impact of percutaneous coronary intervention (PCI) on exercise responses in the coronary circulation, the microcirculation, and systemic hemodynamics in patients with stable coronary artery disease (CAD)?
16. Digesting New Developments in Biosensors - 08/16/2018
 N Engl J Med 2018; 379:686-688
  In a recent article, Mimee, Nadeau, and colleagues tackle this challenge by leveraging the flexibility of synthetic biology and engineering to create a modular, internal, continuous-measurement device that they call the ingestible micro-bio-electronic device (IMBED). They created and tested the device in three steps and showed the utility of their system for measuring heme released from blood within the gastrointestinal tract in a porcine model.
17. Combined Therapy Reduces Infections in the Elderly - 07/10/2018
  A combination therapy fortifies the aging immune system against infections such as flu and pneumonia, according to new clinical trial results.
18. Cancer screening in the United States, 2018: A review of current American Cancer Society guidelines and current issues in cancer screening - 05/30/2018
 CA Cancer J Clin
  Eliminating socioeconomic disparity could prevent one in four cancer deaths in the United States
19. Online, simulation scenarios ready med students for residency - 05/02/2018
 American Medical Association (AMA)
  What medical students know is only as good as how they apply it. Bridging the gap is key to ensuring a successful transition from medical school to residency.
20. Waning Vaccine Protection Contributes to Whooping Cough Comeback - 03/28/2018
  Waning vaccine protection and incomplete vaccinations may be behind a resurgence of whooping cough in the U.S. Semevent / Pixabay A resurgence in whooping cough cases in the U.S. is likely due to incomplete vaccine coverage in the past combined with...
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