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1. Semisynthetic sensor proteins enable metabolic assays at the point of care - 09/14/2018
 Science 14 Sep 2018: Vol. 361, Issue 6407, pp. 1122-1126
  The sensor system successfully generated point-of-care measurements of phenylalanine, glucose, and glutamate. Concentrations of phenylalanine in the blood of phenylketonuria patients were analyzed within minutes with only half a microliter of blood.
2. POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication - 09/11/2018
 Molecular Cell
  Collectively, our study reveals that POLE3-POLE4 possesses intrinsic H3-H4 chaperone activity, which facilitates faithful nucleosome dynamics at the replication fork.
3. Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights - 09/11/2018
 Cell Reports 24(11), 2838-2856
  Our findings suggest an etiological overlap of ASD and SCZ and provide biological insights into these disorders.
4. Population dynamics of normal human blood inferred from somatic mutations - 09/05/2018
 Nature
  Harnessing naturally occurring mutations to report the clonal architecture of an organ enables the high-resolution reconstruction of somatic cell dynamics in humans.
5. Coupling of bone resorption and formation by RANKL reverse signalling - 09/05/2018
 Nature
  RANKL reverse signalling is therefore a potential pharmacological target for avoiding the reduced bone formation associated with inhibition of osteoclastogenesis.
6. New gene-editing treatment might help treat a rare disorder, hints first human test - 09/05/2018
 American Association for the Advancement of Science
  The first test of a new gene-editing tool in people has yielded early clues that the strategy, an infusion that turns the liver into an enzyme factory, could help treat a rare, inherited metabolic disorder.
7. The NORAD lncRNA assembles a topoisomerase complex critical for genome stability - 08/27/2018
 Nature
  Our results demonstrate that the interaction between NORAD and RBMX is important for NORAD function, and that NORAD is required for the assembly of the previously unknown topoisomerase complex NARC1, which contributes to maintaining genomic stability.
8. AMA Studies Show Continued Cost Burden of Medical Liability System - 01/24/2018
 American Medical Association (AMA)
9. AMA Launches New Podcast Series to Tackle Salient Issues in Medicine - 01/16/2018
 American Medical Association (AMA)
10. New Compound Improves Obesity-Related Health Complications in NIH-Led Study - 07/26/2010
 National Institutes of Health (NIH)
11. Science: First Cell Controlled by Synthetic Genome - 05/20/2010
 American Association for the Advancement of Science (AAAS)
  Researchers Are the First to [Boot Up] a Bacterial Cell with a Synthetic Genome
12. Type 2 diabetes associated with a particular profile of intestinal microbiota - 03/15/2010
 American Diabetes Association (ADA)
  Recent evidence has suggested a link between the composition of intestinal microbiota and metabolic diseases. A study conducted at the University of Copenhagen has now demonstrated that type 2 di ...
13. Synthetic DNA: Balancing Reward and Risk - 02/05/2010
 American Association for the Advancement of Science (AAAS)
  Proposed U.S. Guidelines on Synthetic DNA Balance Reward and Risk, Experts Say at AAAS
14. Antibodies Against Abnormal Glycoproteins Identified as Possible Biomarkers for Cancer Detection - 02/02/2010
 National Institutes of Health (NIH)
15. Genetics Web Sites Awarded the First Science Prize for Online Resources in Education - 01/28/2010
 American Association for the Advancement of Science (AAAS)
16. NIGMS Awards Contract to Expand Human Genetic Cell Repository - 01/25/2010
 National Institutes of Health (NIH)
17. Newly Identified Genes Influence Insulin and Glucose Regulation - 01/17/2010
 National Institutes of Health (NIH)
  Five of these variants raise type 2 diabetes risk
18. Diet May Protect Against Gene Changes in Smokers - 01/12/2010
 National Institutes of Health (NIH)
19. Molecule Repairs Alcohol Metabolism Enzyme - 01/10/2010
 National Institutes of Health (NIH)
20. NIDA Researchers Discover a New Mechanism Underlying Cocaine Addiction - 01/07/2010
 National Institutes of Health (NIH)
  Study Offers Promise for Medication Development
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